欧罗拉生物科技

2018精准医疗暨离子通道会议 – 照片和演示文稿下载

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2018精准医疗暨离子通道会议 – 照片和演示文稿

[vc_row_inner css=”.vc_custom_1543995705801{margin-bottom: 15px !important;background-color: #eeeeee !important;}”][vc_column_inner][vc_column_text css=”.vc_custom_1543995891699{border-bottom-width: 15px !important;}”]第一天演讲文稿下载

Natural compounds targeting at ion channels are potential antitumor drugs – Hailong An

Novel Strategies for translational research in pain drug discovery – Andre Ghetti

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摘要：

TRPM2 channel New Drug Targets for Treating Brain Ischemia – Wei Yang

Cancer Vulnerability Unveiled by Targeting Ion Channels_ A Novel Discovery and Therapeutic Approach – Saverio Gentile

Discovery of Novel Natural Products Targeting Ion Channels – Yin Nian

Engineering Mini Human Heart Chambers for Drug Discovery and Disease Modeling – Ronald Li

From fly to mammal targeting ion channels in brain tumor – Xi Huang

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) to model arrhythmogenic diseases – Marc Pourier

Identification of the calcium-dependent gating and targeted-drug discovery of CaCCs – Hailong An

Immunomodulatory peptides from edible plants – George Chandy

Leptin-induced hypothalamic excitability is mediated by a TRPC-Cav3 complex – Erika Piedras-Renteria

Novel Strategies for Translational Research in Pain Drug Discovery – Andre Ghetti

Patient-specific induced pluripotent stems as a platform for precision therapeutics in the treatment of an inherited cardiac arrhythmia – Robert Kass

The application of hiPSC-vCMs generated in the chemical-defined and albumin-free condition in the MEA cardiac safety assessment – Haiheng Dong

The ion channel and transporters gene expression profile indicates a shift in excitability and metabolisms during malignant progression of Follicular Lymphoma – Cesare Sala

TMEM16A inhibition represents a novel therapy for breast cancer with high EGFR expression – Qinghuan Xiao

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第二天演讲文稿下载

Role and therapeutic targeting of T-type calcium channels in glioblastoma – Roger Abounader

Automation of the Differential Digestion Process for Sexual Assault Kit Evidence – Helena Wong

Ion Transporters in Glioma – Dandan Sun

Novel perspectives of ion channels in cancer – Annarosa Arcangeli

Peptide Array for Drug Discovery – Myriame Gabay

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摘要：

Thermal stress promote tumorigenesis in ESCC viaTRPV2 dependent pathway – Rongqi Huang

Automated Differential Digestion using the VERSA 1100 – Helena Wang

Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo – Luigi Leanza

GLI2-regulated ion-channel genes as potential targets of SHH medulloblastoma – Chi-chung Hui

Integrative analysis of pan-cancer genomics datasets reveals prognostic and functional oncochannels – Jüri Reimand

Investigation of TRPM4 and its Role in Cell Migration and Proliferation of Prostate Cancer Cells – Anna Borgström

Ion Transporters in Glioma – Dandan Sun

KCC2 ion transporter as a novel therapeutic target for epilepsy – Jinwei Zhang

Liquid Biopsy_ Connecting the missing links of precision medicine in cancer – Jodie Tang

Na+-K+-2Cl- cotransporter NKCC1 in regulation of glioma migration and progression – Dandan Sun

New targets for fast onset antidepressants – Yang Li

Opening up New Opportunities by Combining High Throughput Electrophysiology with Optical Tools – Andrea Brüggemann

Overriding ‘Ionic-Checkpoint’_ A New Strategy to Boost Antitumour Responses of T Lymphocytes – Navin Verma

Pharmacological validation of new kinase targets with small molecules – Xianming Deng

Role and therapeutic targeting of T-type calcium channels in glioblastoma – Roger Abounader

Screening of high-effective DNA methylation markers for discriminating monozygotic twins – Shujin Li

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第三天演讲文稿下载

Targeting Voltage-Gated Sodium Channels for the Treatment of Epilepsy – Christopher Makinson

Clinical utility of circulating tumour DNA analysis in hormone receptor positive breast cancer patients – Isaac Garcia-Murillas

Mutation Effect, Mechanism and Drug Discovery using Epileptic Patient iPSCs – Hua-Lin Huang

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摘要：

The mechanism underlying protein biogenesis of the hERG channel and pharmacological rescue of LQTS mutant channels – Shiqing Cai

A non-canonical VSD-pore coupling in KCNQ channels – Panpan Hou

Clinical utility of circulating tumour DNA analysis in hormone receptor positive breast cancer patients – Isaac Garcia Murillas

Contribution of membrane receptors to visceral pain sensation – Joel Castro

Design and applications of genetically-encoded ion channel modulators – Henry Colecraft

Discovery of Kv2.1 potassium channel selective blocker for neuroprotection – Weiping Wang

Epigenetic regulations of purinergic P2X receptors under various pain conditions – Guangyin Xu

ERG3 potassium channel-mediated suppression of neuronal intrinsic excitability and prevention of seizure generation in mice – Zhuo Huang

Making novel pain drugs by selectively targeting Nav1 – Lunbin Deng

Mechanosensitive Ion Channel Protein Piezo1 in Vascular Biology – Jing Li

Regulation of MTORC1 by the lysosomal Ca2+ channel TRPML1 mucolipin-1 in cellular homeostasis and human diseases – Xianping Dong

Structure and mechanogating mechanism of the mechanosensitive Piezo channel – Bailong Xiao

Targeting Voltage-Gated Sodium Channels for the Treatment of Epilepsy – Christopher Makinson

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2018精准医疗暨离子通道会议 – 照片和演示文稿

[vc_row_inner css=”.vc_custom_1543995705801{margin-bottom: 15px !important;background-color: #eeeeee !important;}”][vc_column_inner][vc_column_text css=”.vc_custom_1543995891699{border-bottom-width: 15px !important;}”]第一天演讲文稿下载

Natural compounds targeting at ion channels are potential antitumor drugs – Hailong An

Novel Strategies for translational research in pain drug discovery – Andre Ghetti

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摘要：

TRPM2 channel New Drug Targets for Treating Brain Ischemia – Wei Yang

Cancer Vulnerability Unveiled by Targeting Ion Channels_ A Novel Discovery and Therapeutic Approach – Saverio Gentile

Discovery of Novel Natural Products Targeting Ion Channels – Yin Nian

Engineering Mini Human Heart Chambers for Drug Discovery and Disease Modeling – Ronald Li

From fly to mammal targeting ion channels in brain tumor – Xi Huang

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) to model arrhythmogenic diseases – Marc Pourier

Identification of the calcium-dependent gating and targeted-drug discovery of CaCCs – Hailong An

Immunomodulatory peptides from edible plants – George Chandy

Leptin-induced hypothalamic excitability is mediated by a TRPC-Cav3 complex – Erika Piedras-Renteria

Novel Strategies for Translational Research in Pain Drug Discovery – Andre Ghetti

Patient-specific induced pluripotent stems as a platform for precision therapeutics in the treatment of an inherited cardiac arrhythmia – Robert Kass

The application of hiPSC-vCMs generated in the chemical-defined and albumin-free condition in the MEA cardiac safety assessment – Haiheng Dong

The ion channel and transporters gene expression profile indicates a shift in excitability and metabolisms during malignant progression of Follicular Lymphoma – Cesare Sala

TMEM16A inhibition represents a novel therapy for breast cancer with high EGFR expression – Qinghuan Xiao

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第二天演讲文稿下载

Role and therapeutic targeting of T-type calcium channels in glioblastoma – Roger Abounader

Automation of the Differential Digestion Process for Sexual Assault Kit Evidence – Helena Wong

Ion Transporters in Glioma – Dandan Sun

Novel perspectives of ion channels in cancer – Annarosa Arcangeli

Peptide Array for Drug Discovery – Myriame Gabay

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摘要：

Thermal stress promote tumorigenesis in ESCC viaTRPV2 dependent pathway – Rongqi Huang

Automated Differential Digestion using the VERSA 1100 – Helena Wang

Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo – Luigi Leanza

GLI2-regulated ion-channel genes as potential targets of SHH medulloblastoma – Chi-chung Hui

Integrative analysis of pan-cancer genomics datasets reveals prognostic and functional oncochannels – Jüri Reimand

Investigation of TRPM4 and its Role in Cell Migration and Proliferation of Prostate Cancer Cells – Anna Borgström

Ion Transporters in Glioma – Dandan Sun

KCC2 ion transporter as a novel therapeutic target for epilepsy – Jinwei Zhang

Liquid Biopsy_ Connecting the missing links of precision medicine in cancer – Jodie Tang

Na+-K+-2Cl- cotransporter NKCC1 in regulation of glioma migration and progression – Dandan Sun

New targets for fast onset antidepressants – Yang Li

Opening up New Opportunities by Combining High Throughput Electrophysiology with Optical Tools – Andrea Brüggemann

Overriding ‘Ionic-Checkpoint’_ A New Strategy to Boost Antitumour Responses of T Lymphocytes – Navin Verma

Pharmacological validation of new kinase targets with small molecules – Xianming Deng

Role and therapeutic targeting of T-type calcium channels in glioblastoma – Roger Abounader

Screening of high-effective DNA methylation markers for discriminating monozygotic twins – Shujin Li

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第三天演讲文稿下载

Targeting Voltage-Gated Sodium Channels for the Treatment of Epilepsy – Christopher Makinson

Clinical utility of circulating tumour DNA analysis in hormone receptor positive breast cancer patients – Isaac Garcia-Murillas

Mutation Effect, Mechanism and Drug Discovery using Epileptic Patient iPSCs – Hua-Lin Huang

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摘要：

The mechanism underlying protein biogenesis of the hERG channel and pharmacological rescue of LQTS mutant channels – Shiqing Cai

A non-canonical VSD-pore coupling in KCNQ channels – Panpan Hou

Clinical utility of circulating tumour DNA analysis in hormone receptor positive breast cancer patients – Isaac Garcia Murillas

Contribution of membrane receptors to visceral pain sensation – Joel Castro

Design and applications of genetically-encoded ion channel modulators – Henry Colecraft

Discovery of Kv2.1 potassium channel selective blocker for neuroprotection – Weiping Wang

Epigenetic regulations of purinergic P2X receptors under various pain conditions – Guangyin Xu

ERG3 potassium channel-mediated suppression of neuronal intrinsic excitability and prevention of seizure generation in mice – Zhuo Huang

Making novel pain drugs by selectively targeting Nav1 – Lunbin Deng

Mechanosensitive Ion Channel Protein Piezo1 in Vascular Biology – Jing Li

Regulation of MTORC1 by the lysosomal Ca2+ channel TRPML1 mucolipin-1 in cellular homeostasis and human diseases – Xianping Dong

Structure and mechanogating mechanism of the mechanosensitive Piezo channel – Bailong Xiao

Targeting Voltage-Gated Sodium Channels for the Treatment of Epilepsy – Christopher Makinson

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